As the CIN grade increased, there was a gradual augmentation in the average fluorescence intensity (Figure 1), which meant that there was a higher β1 integrin/CD29 concentration in CIN3 samples compared with CIN1 and CIN2 samples or samples without CIN (p = 0.0132). This evidence concerns the gene ITGB1 and cervical squamous intraepithelial neoplasia.