The type 2 response includes other cytokines such as IL-4, IL-13, and IL-5, which regulate tissue regeneration after injury, protect against parasitic helminth infections, and are also typically associated with atopic and allergic disorders, such as allergic rhinoconjunctivitis, food allergy, and eosinophilic esophagitis (EoE). The gene discussed is IL4; the disease is eosinophilic esophagitis.