ADA and plasma cell myeloma: Comparisons with healthy controls have revealed that analysis of these parameters in multiple myeloma patients revealed a substantial increase in levels of AOPP, MDA, adenosine deaminase (ADA), and a marked decrease in total antioxidant capacity (TAC), glutathione, vitamins C and E, as well as antioxidant enzymes in multiple myeloma patients –both before and after treatment [23].