BMI1 and infection: Infection with ST decreased the proliferation genes PCNA, Ki67, and Cyclin; the ISC marker gene Lgr5; the quiescent ISC marker gene Bmi1; the Goblet cell marker gene Muc2; the Paneth cell marker gene Lyz1; and Wnt3a mRNA levels (p < 0.05, Figure 6A–K).