TRPV1 and rheumatoid arthritis: For example, transient receptor potential vanilloid-1 (TRPV1) has been found to be an important transducer of chemical, inflammatory, and neuropathic pain signals, and is expressed in a variety of neuronal and non-neuronal tissues and organs, including chondrocytes, fibroblasts, macrophages, and the dorsal root ganglion (DRG), which play an important role in inflammatory diseases such as OA and rheumatoid arthritis [73,74].