Building upon our prior investigations, wherein we disclosed differential expressions of ORs and TAS2Rs in the orbitofrontal cortex of individuals with AD [6], along with the discovery of OR7A5 expression in the middle frontal gyrus [16], our focus shifted to the CP, where we examined eleven distinct genes: olfactory receptors (OR2K2, OR2H2, OR1L8, OR13A1, OR7A17, and OR7A5), bitter taste receptors (TAS2R14 and TAS2R5), and type 1 taste receptors (TAS1R1, TAS1R2, and TAS1R3). Here, OR1L8 is linked to Alzheimer disease.