MMP2 and primary cutaneous T-cell non-Hodgkin lymphoma: According to our results, the associated MMP-2 gene promotor genotype (GGCCTT) is significantly more frequent in CTCL-IA stage patients compared to all other CTCL groups, including parapsoriasis, with high sensitivity and specificity which seems to reflect the importance of genetic variability in MMP genes in the development of CTCL [8].