Besides a supposed association with multiple sclerosis, association with other phenotypes was found (some type of cirrhosis of the liver, erythematous conditions, benign neoplasms of the thorax, rheumatoid arthritis, juvenile arthritis, Grave’s disease, type 1 diabetes mellitus, systemic lupus erythematosus, and ulcerative colitis), which seems to demonstrate the complex etiologies associated with the HLA-DRB1*1501 loci [12]. Here, HLA-DRB1 is linked to multiple sclerosis.