Only two variants are shared by two unrelated families each; FAM23 and FAM24 with ARVC share variant DSC2:c.133delG, p.Ala45ProfsTer10; and FAM09 and FAM19, with HOCM and DCM, respectively, share variant MYH7:c.4985G>A, p.Arg1662His (Table 2). The gene discussed is DSC2; the disease is familial dilated cardiomyopathy.