IL17A and neoplasm: In contrast, while EMT6-immune mice showed elevated serum levels of IL-6, and augmented tumor invasion after the inclusion of recombinant IL-6 or IL-17 in the collagen gel matrix, the addition of EMT6-immune DLN cells attenuated tumor invasion despite the inclusion of exogenous IL-6/IL-17 in the gel matrix (Figure 4), an effect abolished by the T depletion of DLN.