BDNF and hearing disorder: pFAR4 gene vector human clinical trial for hearing disorders: In August 2020, a pFAR4 plasmid encoding two neurotrophic factors, the brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) proteins, entered a phase I/II clinical trial directed by Prof. G. Housley (UNSW, Sydney) (www.CINGT.info (accessed on 20 December 2023); Table 1 # ACTRN12618001556235).