An example might be a recent study, performed in patients with mental disorders, where the focus of the research was on the parallel quantification of two markers of systemic inflammation, IL-6 and C-reactive protein (CRP), and markers of an impaired intestinal epithelial barrier, including LPS and lipopolysaccharide-binding protein (LBP), intestinal fatty acid binding protein (IFABP), and calprotectin, to identify patterns of biomarkers that correspond to phenotypes characterized by certain types and severities of mental symptoms [119]. This evidence concerns the gene IL6 and psychiatric disorder.