TLR2 and colitis: Furthermore, Jia et al. [139] found that Lactobacillus rhamnosus GG (LGG) could decrease the IL-17+Th17 ratio and increase the CD25+Foxp3+Treg ratio through the TLR2 pathway, reversing the increased Th17/Treg ratio caused by P. gingivalis and alleviating DSS-induced colitis.