It has been shown that women with PCOS have a greater prevalence of abnormal lipid profiles, including increased low-density lipoprotein (LDL) cholesterol and very-low-density lipoprotein (VLDL) cholesterol levels, high serum triglyceride and free fatty acid concentrations, as well as decreased high-density lipoprotein (HDL) cholesterol levels, which are attributed to decreased apolipoprotein A-I (apoA-I) levels [44,45,46]. This evidence concerns the gene APOA1 and polycystic ovary syndrome.