ETV in ovarian cancer cells was able to decrease AGR2 levels, as well as induce autophagy by increasing a key component in its pathway (LC3-B), suppressing cell proliferation, migration, and invasion when used alone, in vitro and in vivo tumor growth and metastasis when used in combination with the antineoplastic drug paclitaxel [30]. The gene discussed is AGR2; the disease is ovarian cancer.