Taking into account the risk factors, no significant differences were found between the study groups in the expression of the tissue inhibitor of metalloproteinases 1 (TIMP-1) genes; this is not consistent with the available literature, because the results of the study by Sundström J. et al. indicated a direct relationship between the levels of TIMP-1 in plasma with all the classic risk factors for cardiovascular disease. Here, TIMP1 is linked to cardiovascular disorder.