The ventricular arrhythmia (VA), atrioventricular block (AVB), and lethality (LET) incidence rates caused by CIR (evaluated by ECG) and serum levels of cardiac lesion biomarkers creatine kinase–MB (CK-MB) and troponin I (TnI) in adult rats pretreated with a saline solution (0.9%) and submitted to CIR (SS + CIR group) were compared to those pretreated with MB (MB + CIR group), OME (OME + CIR group), and the MB + OME combination (MB + OME + CIR group). This evidence concerns the gene MB and otitis media with effusion.