CD8A and neoplasm: For in vivo experiments performed with C57BL/6 mice, 5 cell lines, shVector cells, shVector cells with PDTC treatment, shSTAT1 cells, shSTAT1 cells with PDTC treatment, and shIRF1 cells were subcutaneously inoculated in mice, followed by the intratumoral injection of the CD8+T conditional medium for 2 months and then an examination by tumor and blood (Figure 6L).