Fusions of linc-genes and cancer-associated genes, such as RAD54L (RAD54 like), PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3), MBP (myelin basic protein), PFN2 (profilin 2), MBD2 (methyl-CpG binding domain protein 2), and YES1 (YES proto-oncogene 1, Src-family tyrosine kinase), as well as tumor suppressors SMAD4 (SMAD family member 4) and SDHA (succinate dehydrogenase complex flavoprotein subunit A), can be an additional factor in cancer promotion. This evidence concerns the gene PIK3C3 and cancer.