Using CPTAC, we analyzed the protein expression levels in HNSCC tissue compared to normal tissue, and we were able to see that for the galectins with higher impact on HNSCC survival, the following galectins Gal-1, Gal-3BP, and Gal-4 were overexpressed in HNSCC. The gene discussed is GAL; the disease is head and neck squamous cell carcinoma.