Otherwise, cytokine synthesis inhibitory factor/T-cell growth inhibitory factor/IL-10 CSIF:TGIF(IL-10), via an in silico database search http://biogps.org/#goto=genereport&id=3586 (Accessed on 9 November 2023), is an anti-inflammatory cytokine, and its promoter polymorphism has been previously associated with susceptibility to POAG [11]. The gene discussed is IL10; the disease is open-angle glaucoma.