ROC curve analysis (Table 3, Figure 2) was performed for B-cell subsets, BSF-2(IL-6), CSIF:TGIF(IL-10), and the BSF-2(IL-6) to CSIF:TGIF(IL-10) ratio to determine the diagnostic performance of these parameters in POAG patients. This evidence concerns the gene IL6 and open-angle glaucoma.