Regarding anxiety, the initial data showed a robust correlation (p < 0.01) with positivity for LA (0.330) and anti-ribosome P antibodies (0.312, p < 0.05), as well as low C3 (0.263, p < 0.05) and low C4 (0.293, p < 0.05), and anti-SM antibodies (0.247, p < 0.05). This evidence concerns the gene C3 and Anxiety.