Resveratrol (2.5 μM) also prevented tumor microenvironment-induced p65-NF-κB phosphorylation and nuclear translocation, which is linked to modifications in the expression patterns of EMT biomarkers (slug, vimentin, E-cadherin), factors related to metastasis (CXCR4, MMP-9, FAK) and apoptosis (caspase-3) [170]. This evidence concerns the gene PTK2 and neoplasm.