Yu et al. [41] also reported a decreased ratio of reduced glutathione (GSH) to oxidized glutathione (GSSG), catalase (CAT), glutathione reductase (GR), and SOD levels in SK-N-SH (human neuroblastoma) and COS-7 (African green monkey kidney fibroblast-like) cells transfected with full-length ATXN3 with 78 CAG repeats (SK-N-SH-MJD78 and COS7-MJD78-GFP; GFP green fluorescent protein), lower than that of wild-type (WT) cells. Here, GSR is linked to neuroblastoma.