A study conducted by Wu et al. observed that C/B6 decreased fecal calprotectin and reduced tumor multiplicity and the total tumor burden, and also downregulated colonic phosphatidylinositol-4,5-bisphosphate 3-kinases (PI3Ks), Wnt, and NF-κB signaling [118]. This evidence concerns the gene NFKB1 and neoplasm.