SLC7A11 and hepatocellular carcinoma: Another work in hepatocellular carcinoma cells demonstrated that IFNγ treatment sensitized Bel7402 and HepG2 cells to ferroptosis inducers (erastin or RSL3) by reducing the GSH content and increasing lipid peroxidation mediated by the JAK/STAT pathway that reduced mRNA/protein expression of SLC3A2 and SLC7A11, consequently inhibiting system Xc- activity, provoking ROS increase and ΔΨm decrease.