HSPH1 and gastric adenocarcinoma: HSPH1 silencing in gastric adenocarcinoma AGS cells stably overexpressing ATF2 showed downmodulation of SLC7A11 at the protein but not at the mRNA level, thus highlighting that HSPH1 can interact with and improve SLC7A11 stability in GC cells, thus contributing to the uptake of cystine required for GSH synthesis [301].