For example, the protein DJ-1/PARK7, an anti-oxidative stress gene, protects cancer cells from ferroptosis by preserving the activity of S-adenosyl homocysteine hydrolase, a hydrolase specific for S-adenosyl-L-homocysteine that produces homocysteine, hence maintaining cysteine synthesized from the TSP pathway by fueling GSH synthesis [227]. This evidence concerns the gene PARK7 and cancer.