NLRP3 and type 2 diabetes mellitus: An Egyptian study investigated NLRP3 expression levels in peripheral blood in T2DM patients with normo-, micro-, and macroalbuminuria and healthy controls (15 subjects per each group) and correlated them with the serum marker of oxidative-stress-related DNA damage 8-OHdG, a marker of inflammation IL1B and urinary heat shock protein 72 (uHSP72), and found them all increased in macroalbuminuric T2DM patients when compared to the other groups [66].