CD8+ T-cell count: reduced risk [41], not predictive [56]CD4+ T-cell, regulatory T-cell count: not predictive [41,56]CD8+CD38+Ki67+ T-cell expansion: positive predictor in NSCLC, but not in malignant melanoma [57]Ki67+ Treg-cell expansion: positive predictor in malignant melanoma, but not in NSCLC [57]. The gene discussed is CD4; the disease is melanoma.