TGFB2 and central nervous system cancer: TGFB1 and TGFB2 have been identified as the most highly expressed tumor-promoting cytokine in the TME of gliomas [47,48,49,50,51,52], prompting us to characterize the abundance of TGFB1 and TGFB2 mRNA addition to the upregulation of TAM cell surface markers.