Women at high risk of breast cancer (such as carriers of BRCA1/2 mutations, women with personal or family history of breast cancer or tumor syndromes such as Li–Fraumeni or Cowden) or with chest radiation therapy administered between 10–30 years of age are recommended to receive breast MRI and yearly mammogram screening starting at age 30 [52]. This evidence concerns the gene BRCA1 and breast carcinoma.