BRCA2 and non-small cell lung carcinoma: BRCA2 may be associated with adenocarcinoma given that eight BRCA2 PGV carriers with NSCLC in one study had this subtype of NSCLC [50], and that in the over 300 patients with NSCLC studied in the SAFIR02-lung trial, the only two identified BRCA2 PGV carriers had adenocarcinoma [46].