SMARCA4 and undifferentiated carcinoma: Other important mutations to note that it could be worth investigating the prevalence of among Hispanics given their associations with anaplastic transformation outside of TERT-promoter mutations include subunits of the SWI/SNF complex such as SMARCA4 and alterations of the PIK3CA gene, which were found to be positive in 33% of thyroid tumor samples with a heterogenous pathology of papillary and anaplastic carcinoma components [47].