1-(4-(methylsulfonyl)phenyl)-3-(phenylthio)-3-(p-tolyl)propane-1-one and its coadministration with curcumin effectively reduced the activity of the NF-κB signaling pathway, leading to a reduced inflammatory response in the environment of cancer cells, and might be considered an effective remedy for the suppression of inflammatory processes in MDA-MB-231 and SKOV3 cell lines [95]. The gene discussed is NFKB1; the disease is cancer.