In adults with T2DM, GLP-1 receptor agonists (GLP-1 RAs) have been shown to have several positive effects through improving glycemic control, reducing appetite, and inducing weight loss through lowering subcutaneous and visceral fat levels [13], as well as reducing risk for cardiovascular events through anti-inflammatory mechanisms [12,14,15]. This evidence concerns the gene GCG and type 2 diabetes mellitus.