We assessed the enrichment scores of MUC family mutated- and wildtype- cohorts in immune cells i.e., CD8+ T cells, CD4+ T cells, dendritic cells, myeloid-derived suppressor cells (MDSCs), macrophages, B cells, neutrophil cells, NK, and Treg cells in COAD. The gene discussed is CD4; the disease is colon adenocarcinoma.