This observation supports the extensive literature showing a crucial role for CD8+ T cells in destructing of \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\beta$$\end{document}βcells during T1DM pathogenesis [61, 65–67]. This evidence concerns the gene CD8A and type 1 diabetes mellitus.