Interestingly, NK, Treg, CD8+ T cells comprised the top three cell types in terms of number of DEGs in T1DM (Fig. 3b), and \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$> 300$$\end{document}>300 genes were upregulated in each of these cell types. This evidence concerns the gene CD8A and type 1 diabetes mellitus.