Moreover, the NF-κB signaling pathway has been implicated in immunosuppression and immune evasion in ovarian cancer cells partly via NFκB-dependent production of IL-6, which impairs DCs but generates and recruits immunosuppressive MDSCs, and IL-8, which increases the expression of the immunosuppressive enzyme arginase [102]. Here, NFKB1 is linked to ovarian cancer.