BNIP3 and myocardial ischemia: Furthermore, this study suggests that the seven mitophagy-signature genes (HSP90AA1, RPS27A, EEF2, EIF4A1, EIF2S1, HIF-1α, BNIP3) may serve not only as potential biomarkers for myocardial ischemia–reperfusion but also as potential targets for future research and Paving the way for novel therapeutic approaches targeting myocardial ischemia–reperfusion injury.