Dr. Strand and his team have investigated the cellular anatomy of the adult human prostate using single-cell RNA sequencing (scRNA-Seq) and reported two novels discovered epithelial cell types: the urothelial origin club (SCGB1A1+) and hillock (KRT13+) cells, other than the known luminal and basal epithelial cells from the human prostate, the number of Club cells increases in BPH compared to normal prostate, but Hillock cell number decreases [30, 35]. The gene discussed is SCGB1A1; the disease is benign prostatic hyperplasia.