Compared with those in the Sham group, the expression levels of GPX4 and xCT in the I/R group were lower (P < 0.05); compared with those in the I/R group, the expression levels of GPX4 and xCT in the Fer-1 group were higher (P < 0.05); compared with those in the I/R group, the expression levels of GPX4 and xCT in the SAS group were lower (P < 0.05); and compared with those in the I/R + SAS group, the expression levels of GPX4 and xCT in the I/R + SAS + FER-1 group were higher (P < 0.05). Here, GPX4 is linked to SATB2 associated disorder.