S100A8 and hydrops fetalis: Two-sample MR analysis showed a genetically instrumented per-SD S100A8/A9 was associated with higher odds of post-AMI HF in Wald ratio analysis (OR: 2.06 [95% CI: 1.25–3.39]; P = 0.004) and inverse-variance-weighted (IVW) analysis (OR: 1.55 [95% CI: 1.15–2.09]; P = 0.004) (Table 3).