AKT1 and breast carcinoma: This association was mediated through miR-155 inhibiting the upstream inhibitor of c-MYC, FOXO3a, thereby initiating activation of c-MYC (PIK3R1-PDK/AKT-FOXO3a-cMYC pathway) and highlighting the pivotal role of miR-155 in regulating glucose metabolism in breast cancer [90].