Conditional deletion of SMAD1/5/4 exclusively in the cells from mesenchymal lineage (including uterine stroma) using anti-Mullerian hormone type 2 receptor cre (Amhr2-cre) results in infertility with defective decidualization (Pangas et al., 2008; Rodriguez et al., 2016). This evidence concerns the gene AMHR2 and Infertility.