NUPR1 and breast carcinoma: Similarly, in other datasets GSE12093 (Zhang et al., 2009; Figure 4E) and GSE16391 (Desmedt et al., 2009), chemotherapy-treated breast cancer patients with significantly lower survival rates expressed higher level of NUPR1 (p=0.027 and 0.0003, respectively; Figure 4—figure supplement 1A), suggesting that high NUPR1 expression is associated with poor clinical outcomes among TNBC patients.