The injection of Cd-O2/N2 atomized gas further significantly inhibited COX-2 expression within these colon tumors (C-Blank: p < 0.01; C-Control: p < 0.05), but the effect on COX-2 expression in the colon mucosa of the CC mice that had been implanted with intestinal stents was not significant. Here, PTGS2 is linked to colonic neoplasm.