IL6 and Sepsis: In late-onset sepsis, Ng et al. serum IL-6 concentrations quickly fall to undetectable values during antibiotic treatment, and the high sensitivity (98%) and negative predictive values (98%) of IL-6 and CRP (together considered) indicated that antibiotics could be confidently discontinued at 48 h without waiting for microbiological results, providing that the infants are in good clinical condition [36].