CALCA and Sepsis: The current PROABIS Study (Procalcitonin and Duration of Anti-Biotic therapy In Late Onset Sepsis of Neonate) is a multicenter randomized controlled open trial comparing the efficacy of a PCT guided strategy (superiority aspect) and safety (non-inferiority aspect) versus usual strategy in LOS of the neonate, still recruiting neonates in France at time of writing (Clinical Trials ID: NCT03730636).