Alexandre et al. [18] reported the presence of OXA and OX1R in two cancer cell lines, the androgen-responsive cell line LNCaP and the androgen-unresponsive cell line AI DU 145, in benign prostate hyperplasia (BPH) and in cancer of the prostate (CaP) at various stages. This evidence concerns the gene HCRTR1 and Familial prostate cancer.