Therefore, we investigated the overlap between these human orthologues of canine DEGs in anti-canine-IgE reactions at 6 and 24-h and a previously published transcriptome skin data from acute spontaneous human AD skin lesions using criteria of −1.5 ≥ FC ≥ 1.5 and FDR < 0.05. Here, IGHE is linked to Alzheimer disease.