Table 3 summarizes the studies reporting infections in patients with IPEX syndrome. These patients also predominantly develop staphylococcal sinopulmonary infections as well as candidal infections. Rapamycin, which is an mTOR inhibitor, is a targeted therapy for the management of immunological complications in IPEX. It helps in the restoration of Treg cell function in IPEX patients [27]. This evidence concerns the gene MTOR and immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome.