They used a proteoform approach and OB proteomics datasets derived from subjects with AD, PD, mixed dementia, dementia with Lewy bodies, frontotemporal lobar degeneration (FTLD-TDP43), progressive supranuclear palsy (PSP), and amyotrophic lateral sclerosis (ALS), were compared and integrated. Here, TARDBP is linked to amyotrophic lateral sclerosis.