Given the substantial agreement between dyslipidemia identified through traditional lipid tests and high CVD risk indicated by ApoB levels, and the potential to identify more patients at risk with ApoB testing, this study highlights the significant role ApoB testing can play in improving the detection of individuals at high-risk for CVD within the Korean adult population, particularly those with normal results from traditional lipid panels. The gene discussed is APOB; the disease is metabolic syndrome.